2022年9月26-28日，第一次欧洲替代动物实验大会（3R大会）及第23届EUSAAT年会将在奥地利林茨召开。欧洲替代动物实验学会（the European Society for Alternatives to Animal Testing，EUSAAT）是全欧洲的3R学会。致力于根据3Rs原则（替代、减少和优化）保护实验动物。

会议议题

替代-Replacement

• Disease models and microphysiological systems

• Emerging technologies: stem cells incl. hiPSCs, bioprinting, spheroids, organoids, multi-organ models, “-omics” analysis, systems biology approaches, IT and big data

• Biological barriers: e.g. lung, gut, kidney & skin epithelia, blood-brain & blood-saliva barriers

• Animal-free human based cell culture – replacement of serum, matrigel, gelatin, collagens, trypsin, S9, etc. – and recombinant antibodies

• Good cell culture practice

• Development and implementation of Novel Approach Methodologies (NAMs)

• In silico models: toxicology & efficacy of drugs, chemicals & cosmetics, new approaches for biomedical research

• In vitro toxicology: Specific endpoints of toxicity, alternatives to animal testing in food safety and nutrition, Neurotoxicity & Developmental Neurotoxicity (DNT) and Ecotoxicology

• Efficacy and safety testing of drugs, medical devices, biopharmaceutics, cosmetics, consumer products (e. g. toys) and chemicals (REACH & alternatives)

减少-Reduction

• Preregistration, reporting, and experimental design

• Organ and tissue sharing and approaches to reduce surplus animals

• Translational aspects (species differences) and reproducibility

优化-Refinement

• Best practice approaches and culture of care

• Avoidance of severe suffering and pain management/assessment

• Cage enrichment and non-invasive handling

• COVID-19 pandemic and the 3Rs: in vitro models, vaccine development and drug testing

• 3Rs in education and academia

• 3Rs centres and platforms in Europe & international, national and local centres

• 3Rs and policy: Implementing 3Rs guidelines and concepts, Novel Approach Methodologies (NAMs) and Directives – Ethical and legal issues – Cosmetics testing ban (and REACH)

• “Young Scientists” session

• Publication policies – ARRIVE guidelines & Co

摘要

截止日期：6月20日

大会官网：Congress 2022 - EUSAAT  https://eusaat.eu/eusaat-congress/23rd-edition/congress-2022/