2009年最热门论文（被引次数最多）排行
科学观察（Science Watch）网站近日回顾了2009年的最热门研究，评出了09年最热门论文（被引次数最多）排行。
在作者排行中，排在首位的为麻省理工学院白头研究所的Rudolf Jaenisch教授，自2008年以来他共发表了14篇热门论文，他主要从事表观遗传学方面的研究，在胚胎干细胞和iPS细胞研究领域取得多项进展。华人科学家东华大学何吉欢教授以10篇热门论文排在前10位，他提出了变分迭代算法以及一些新的非线性分析方法等。
在期刊方面，前44篇热门论文中，《新英格兰医学杂志》（New England Journal of Medicine）发表了其中的11篇，位居第一。
另外上榜的还有英国曼彻斯特大学Andre K. Geim和他的同事Konstantin Novoselovud关于石墨烯的研究；麻省总医院Mark J. Daly在全基因组关联方面的研究；Broad研究所的创始人之一、著名遗传学家Eric S. Lander有关基因分析及肺癌和多发性硬化症的研究；俄亥俄州立大学Carlo M. Croce研究了微RNA在治疗结肠癌、白血病和其他恶性肿瘤中的作用；最后一位是日本大阪大学免疫学家Shizuo Akira，在先天免疫研究方面成果突出。
表一 2009年发表的最热门论文排行
| The Red-Hot Research Papers of 2009 | ||
| Rank |
Paper |
Citations |
| 1 | E. Komatsu, et al., "Five-year Wilkinson Microwave Anisotropy Probe observations: Cosmological interpretation," Astrophys. J. Suppl. Ser., 180(2): 330-76, February 2009. | 659 |
| 2 | J. Dunkley, et al., "Five-year Wilkinson Microwave Anistropy Probe observations: Likelihoods and parameters from the WMAP data," Astrophys. J. Suppl. Ser., 180(2): 306-29, February 2009. | 274 |
| 3 | O. Adriani, et al., "An anomalous positron abundance in cosmic rays with energies 1.5-100 GeV," Nature, 458(7238): 607-9, 2 April 2009. | 173 |
| 4 | W. Duckworth, et al., "Glucose control and vascular complications in veterans with type 2 diabetes," New Engl. J. Med., 360(2): 129-39, 8 January 2009. | 172 |
| 5 | G. Hinshaw, et al., "Five-year Wilkinson Microwave Anisotropy Probe observations: Data processing, sky maps, and basic results," Astrophys. J. Suppl. Ser., 180(2): 225-45, February 2009. | 171 |
| 6 | F.H. Schröder, et al., "Screening and prostate-cancer mortality in a randomized European study," New Engl. J. Med., 360(13): 1320-8, 26 March 2009. | 148 |
| 7 | Novel Swine-Origin Influenza A ( H1N1) Virus Investigation Team (F.S. Dawood, et al.), "Emergence of a novel swine-origin influenza A (H1N1) virus in humans," New Engl. J. Med., 360(25): 2605-15, 18 June 2009. | 141 |
| 8 | N. Arkani-Hamed, et al., "A theory of dark matter," Phys. Rev. D, 79(1): No. 015014, January 2009. | 137 |
| 9 | G.L. Andriole, et al., "Mortality results from a randomized prostate-cancer screening trial," New Engl. J. Med., 360(13): 1310-9, 26 March 2009. | 130 |
| 10 | J.L. Mega, et al., "Cytochrome P-450 polymorphisms and response to clopidogrel," New Engl. J. Med., 360(4): 354-62, 22 January 2009. | 120 |
| 11 | S. Finfer, et al., "Intensive versus conventional glucose control in critically ill patients," New Engl. J. Med., 360(13): 1283-97, 26 March 2009. | 109 |
| 12 | O. Adriani, et al., "New measurement of the antiproton-to-proton flux ratio of up to 100GeV in the cosmic radiation," Phys. Rev. Lett., 102(5): No. 051101, 6 February 2009. | 108 |
| 13 | K.S. Kim, et al., "Large-scale pattern growth of graphene films for stretchable transparent electrodes," Nature, 457(7230): 706-10, 5 February 2009. | 102 |
| 14 | S.M. Lippman, et al., "Effect of selenium and vitamin E on risk of prostate cancer and other cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)," JAMA, 301(1): 39-51, 7 January 2009. | 102 |
| 15 | D.C. Elias, et al., "Control of graphene’s properties by reversible hydrogenation: Evidence for graphane," Science, 323(5914): 610-3, 30 January 2009. | 96 |
| 16 | Z. Ahmed, et al., "Search for weakly interacting massive particles with the first five-tower data from the Cryogenic Dark Matter Search at the Soudan Underground Laboratory," Phys. Rev. Lett., 102(1): No. 011301, 9 January 2009. | 95 |
| 17 | M. Cirelli, "Model-independent implications of the e(+/-), P (over-bar) cosmic ray spectra on properties of Dark Matter," Nucl. Phys. B, 813(1-2): 1-21, 21 May 2009. | 95 |
| 18 | C. Fraser, et al., "Pandemic potential of a strain of influenza A (H1N1): Early findings," Science, 324(5934): 1557-61, 19 June 2009. | 93 |
| 19 | C.J. Willer, et al., "Six new loci associated with body mass index highlight a neuronal influence on body weight regulation," Nature Genetics, 41(1): 25-34, January 2009. |
91 |
| 20 | A. Gustavsson, "Algebraic structures on parallel M2 branes," Nucl. Phys. B, 811(1-2): 66-76, 11 April 2009. |
89 |
| 21 | T. Simon, et al., "Genetic determinants of response to clopidogrel and cardiovascular events," New Engl. J. Med., 360(4): 363-75, 22 January 2009. | 85 |
| 22 | M.R. Nolta, et al., "Five-year Wilkinson Microwave Anisotropy Probe observations: Angular power spectra," Astrophys. J. Suppl. Ser., 180(2): 296-305, February 2009. | 84 |
| 23 | K. Woltjen, et al., "piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells," Nature, 458(7239): 766-70, 9 April 2009. | 83 |
| 24 | P.M. Ho, et al., "Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome," JAMA, 301(9): 937-44, 4 March 2009. | 81 |
| 25 | A.A. Abdo, et al., "Measurement of the cosmic ray e+ + e- spectrum from 20 GeV to 1 TeV with the Fermi Large Area Telescope," Phys. Rev. Lett., 102(18): No. 181101, 8 May 2009. | 80 |
| 26 | V. Cvetkovic, et al., "Multiband magnetism and superconductivity in Fe-based compounds," EPL, 85(3): No. 37002, February 2009. | 80 |
| 27 | P. Horava, "Quantum gravity at a Lifshitz point," Phys. Rev. D, 79(8): No. 084008, April 2009. | 77 |
| 28 | P.W. Serruys, et al., "Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease," New Engl. J. Med., 360(10): 961-72, 5 March 2009. | 77 |
| 29 | M. Paez-Ribes, et al., "Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis," Cancer Cell, 15(3): 220-31, 3 March 2009. | 77 |
| 30 | S.H. Park, et al., "Bulk heterojunction solar cells with internal quantum efficiency approaching 100%," Nature Photonics, 3(5): 297-302, May 2009. | 70 |
| 31 | G. Thorleifsson, et al., "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity," Nature Genetics, 41(1): 18-24, January 2009. | 70 |
| 32 | K. Kaji, et al., "Virus-free induction of pluripotency and subsequent excision of reprogramming factors," Nature, 458(7239): 771-5, 9 April 2009. | 69 |
| 33 | P.L. Alireza, et al., "Superconductivity up to 29 K in SrFe2As2 and BaFe2As2 at high pressures," J. Physics- Condensed Matter, 21(1): No. 012208, 7 January 2009. | 69 |
| 34 | A. Reina, et al., "Large area, few-layer graphene films on arbitrary substrates by chemical vapor deposition," Nano Letters, 9(1): 30-5, January 2009. | 69 |
| 35 | F. Soldner, et al., "Parkinson’s disease patient-derived induced pluripotent stem cells free of viral reprogramming factors," Cell, 136(5): 964-77, 6 March 2009. | 68 |
| 36 | J.Y. Yu, et al., "Human induced pluripotent stem cells free of vector and transgene sequences," Science, 324(5928): 797-801, 8 May 2009. | 67 |
| 37 | J.M.L. Ebos, et al., "Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis," Cancer Cell, 15(3): 232-9, 3 March 2009. | 66 |
| 38 | A. Garber, et al., "Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomized, 52-week, phase III, double-blind, parallel-treatment trial," Lancet, 373(9662): 473-81, 7 February 2009. | 65 |
| 39 | R.J. Garten, et al., "Antigenic and genetic characteristics of the swine-origin 2009 A(H1N1) influenza viruses circulating in humans," Science, 325(5937): 197-201, 10 July 2009. | 64 |
| 40 | F. Wang, et al., "Functional renormalization-group study of the pairing symmetry and pairing mechanism of the FeAs-based high-temperature superconductor," Phys. Rev. Lett., 102(4): No. 047005, 30 January 2009. | 64 |
| 41 | J. Tol, et al., "Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer," New Engl. J. Med., 360(6): 563-72, 5 February 2009. | 63 |
| 42 | T.E. Klein, et al., "Estimation of the warfarin dose with clinical and pharmacogenetic data," New Engl. J. Med., 360(8): 753-64, 19 February 2009. | 62 |
| 43 | J.P. Collet, et al., "Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study," Lancet, 373(9660): 309-17, 24 January 2009. | 61 |
| 44 | B.C. Fellstrom, et al., "Rosuvastatin and cardiovascular events in patients undergoing hemodialysis," New Engl. J. Med., 360(14): 1395-1407, 2 April 2009. | 60 |
表二 近2年来最丰产的热门论文作者排行
| Scientists with Multiple Hot Papers | |||
| Name |
Institution |
Field |
Number of Hot Papers |
| Rudolf Jaenisch | Whitehead Institute, MIT | Biochemistry | 14 |
| Mark J. Daly | Broad Institute of Harvard and MIT, and Massachusetts General Hospital | Genetics | 13 |
| Andre K. Geim | University of Manchester | Materials | 13 |
| David Altshuler | Broad Institute of Harvard and MIT, and Massachusetts General Hospital | Genetics | 13 |
| Konstantin Novoselov | University of Manchester | Materials | 12 |
| Carlo M. Croce | Ohio State University | Cancer Genetics | 12 |
| Goncalo Abecasis | University of Michigan | Biostatistics | 10 |
| Eric S. Lander | Broad Institute of MIT and Harvard | Genomics | 10 |
| Mikhail Katsnelson | Radboud University of Nijmegen | Materials | 10 |
| Ji-Huan He | Donghua University | Mathematics | 10 |
| Paul I.W. de Bakker | Broad Institute of MIT and Harvard | Genetics | 9 |
| Shizuo Akira (see also | see also) |
Osaka University | Immunology | 9 |
在热门论文排行中，物理科学领域的成果引人注目，其中威尔金森微波各向异性探测器发挥了很大作用。另外，宇宙射线和暗物质也是热门话题。
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