产品编号KMPH1835

产品名称Recombinant Human ACE2 Protein, His-tag

规格100ug, 1mg

物种Human

宿主HEK293 Cells

内毒素水平< 1.0 EU per μg of the protein as determined by the LAL method.

缓冲体系Lyophilized from sterile PBS, pH 7.4.

纯化方式His Tag Purification

产品背景Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell membranes of cells located in the lungs, arteries, heart, kidney, and intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin (1–7). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7), making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses, including HCoV-NL63, SARS-CoV, and SARS-CoV-2.

保存条件Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.