anymaze动物行为整体实验室 动物行为学实验站 动物行为学视频分析系统 动物行为学工作站
ANY-maze动物行为学实验室
一、实验室介绍
ANYmaze动物行为学实验室采用美国Stoelting公司生产的ANYmaze动物行为分析软件，硬件由江苏赛昂斯生物科技有限公司设计生产，完全无缝对接，中外结合，性价比最优！我司为您提供专业的实验室前期设计施工、技术支持、产品培训和良好的售后服务，确保您的实验室布局合理，功能完备。ANY-maze动物行为视频分析系统是一套通过视频摄像机和计算机，采用图像处理技术，自动跟踪和记录动物行为的通用型运动轨迹记录分析系统，可以应用在神经药理，学习记忆药理，抗衰老药理和新药神经系统一般药理毒理研究，也可用于神经科学基础研究。
二、实验应用
ANY-maze适用于morris水迷宫实验、开场实验、旷场实验、自发活动、悬尾实验、强迫游泳实验、明暗箱实验、T型迷宫、Y型迷宫、放射型迷宫、高架十字迷宫、八臂迷宫、Barnes迷宫、条件性位置偏爱实验、Zero迷宫、孔洞实验、新物体识别、社会交互实验等几乎所有的动物行为实验。
ANY-maze行为分析系统不但可以用于大小鼠、猫、犬、兔、豚鼠等小动物行为活动的跟踪监测，还可用于鱼、线虫、果蝇等微小生物行为活动的跟踪监测。
三、软件特点
支持三点识别（头部、重心、尾部）与轮廓识别同时实验，可探测动物的趋向轨迹，目标跟踪稳定可靠
测量精确，分析指标全面丰富，提供所在区域内的活动轨迹、时间、距离、潜伏期、速度、动/静状态等
在线实时图像分析和视频录像文件分析
采用极具人性化的树状结构体系，每个操作步骤均有详细对应的设置说明
多种实验启动/结束方式，方便实验操作
自带事件统计和分析功能
具有综合的报告和分析功能，自带超过30多种的统计检验
空间分辨率640×480，数字压缩录像功能
支持平均分段和任意分段方式查看统计实验数据
可以通过自定义事件（Event）和行为（Action），来完成各种复杂的实验程序控制
软件提供四种实验模式：视频轨迹模式、Freezing监测模式、No Tracking模式、No video模式
软件内置ANYmaze视频转换器，转换后支持所有的视频格式的离线分析。
四、实验室分类
学习记忆实验室
主要包括仪器有：Morris水迷宫、Barnes迷宫、穿梭实验系统、避暗实验系统、跳台实验系统、八臂迷宫和、Y迷宫、T迷宫等。
焦虑抑郁实验室
主要包括仪器有：高架十字迷宫、O迷宫、强迫游泳实验、悬尾实验、学习无助系统、饮水点击冲突系统等。
神经精神实验室
主要包括仪器有：自发活动实验、旷场实验、洞板实验系统、联合开场、斯金纳箱、场景恐惧系统、震惊实验系统等。
药物成瘾实验室
主要包括仪器有：大小鼠CPP条件性位置偏爱实验系统、CPA条件厌恶系统、自身给药系统等。
运动协调实验室
主要包括仪器有：大小鼠步态行为分析系统、转棒式疲劳仪、动物实验跑台等。
五、实验室布局
实验室布局根据客户需求及实际场地设计，下图为国内某客户的布局图： 
六、指标参数
参数名称 | 总 | 自定义区域 | 百分比 | 首次进入 |
路程 | √ | √ | √ | × |
运动时间 | √ | √ | √ | √ |
静止时间 | √ | √ | √ |
|
进入次数 | √ | √ | × | × |
其他参数 | 理毛次数、僵直次数、僵直持续时间、运动轨迹 使用Anymaze软件发表论文列表（部分） 1、 Lee JY et al. (2009) Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus. Nature Medicine 15:91-96影响因子：27.553
2、 Belforte JE et al. (2009) Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nature Neuroscience (advanced online publication) 影响因子：14.345
3、 Imbimbo BP et al. (2010) CHF5074, a Novel γ-Secretase Modulator, Restores Hippocampal Neurogenesis Potential and Reverses Contextual Memory Deficit in a Transgenic Mouse Model of Alzheimer’s Disease. Journal of Alzheimer’s Disease 20: 159–173 影响因子：5.101
4、 Moore AH et al. (2009) Sustained expression of interleukin-1β in mouse hippocampus impairs spatial memory. Neuroscience 64:1484-95. 影响因子：3.556 5、 Pathipati P et al. (2009) Delayed and chronic treatment with growth hormone after endothelin-induced stroke in the adult rat. Behavioural Brain Research 204:93-101影响因子：3.171
6、 Epp JR and Galea LAM (2009) Hippocampus-dependent strategy choice predicts low levels of cell proliferation in the dentate gyrus. Neurobiology of Learning and Memory 91:437-446影响因子：3.757
7、 Frye CA and Paris JJ (2009) Infusions of bicuculline to the ventral tegmental area attenuates sexual, exploratory, and anti-anxiety behavior of proestrous rats. Pharmacology Biochemistry and Behavior 93:474-481影响因子：2.751
8、 Cline MA et al. (2009) LPLRFamide causes anorexigenic effects in broiler chicks and Bobwhite quail. General and Comparative Endocrinology 165:315-320 影响因子：2.654
9、 Layne JE et al. (2009) Central calcitonin exerts anoretic effects via the hypothalamus in chicks. Pharmacology Biochemistry and Behavior 92:433-438 影响因子：2.751
10、Llaneza DC and Frye CA (2009) Progestogens and estrogen influence impulsive burying and avoidant freezing behavior of naturally cycling and ovariectomized rats. Pharmacology Biochemistry and Behavior 93:337-342 影响因子：2.751
11、Janes AC et al. (2009) The involvement of type IV phosphodiesterases in cocaine-induced sensitization and subsequent pERK expression in the mouse nucleus accumbens. Psychopharmacology 206:177-185影响因子：3.676 12、Peric-Mataruga V (2009) Effects of ghrelin on the feeding behavior of Lymantria dispar L. (Lymantriidae) caterpillars. Appetite 53:147-150 影响因子：2.341
13、Booker L et al. (2009) Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception. Drug and Alcohol Dependence 105:42-47 影响因子：3.371
14、Thomas MB et al. (2009) Sex-specific susceptibility to cocaine in rats with a history of prenatal stress. Physiology & Behavior 97:270-277 影响因子：2.806
15、Capsoni S et al et al. (2009) Delivery of NGF to the Brain: Intranasal versus Ocular Administration in Anti-NGF Transgenic Mice. Journal of Alzheimer's Disease 16:371-388 影响因子：5.101
16、Cline MA et al. (2009) Satiety induced by central stresscopin is mediated by corticotrophin-releasing factor receptors and hypothalamic changes in chicks. Pharmacology Biochemistry and Behavior 92:663-669 影响因子：5.101
17、Walf AA and Frye CA (2009) Effects of two estradiol regimens on anxiety and depressive behaviors and trophic effects in peripheral tissues in a rodent model. Gender Medicine 6:300-311
18、Kourrich S and Thomas MJ (2009) Similar neurons, opposite adaptations: psychostimulant experience differentially alters firing properties in accumbens core versus shell. J Neuroscience 29:12275-12283影响因子：7.452
19、Covaceuszach Sonia et al. (2009) Development of a Non Invasive NGF-Based Therapy for Alzheimer's Disease. Current Alzheimer Research 6:158-170影响因子：4.132
20、Zhao W and Becker JB (2009) Sensitization enhances acquisition of cocaine self-administration in female rats: Estradiol further enhances cocaine intake after acquisition. Hormones and Behavior In Press影响因子：3.876
21、Schlosburg JE et al. (2009) Endocannabinoid modulation of ccratching response in an acute allergenic model: a new prospective neural therapeutic target for Pruritus. Journal of Pharmacology And Experimental Therapeutics 329:314-323影响因子：4.309
22、Guzmán CB et al. (2009) Sex-dependent effect of cyclooxygenase-2 inhibition on mouse spatial memory. Behavioural Brain Research 99:355-9影响因子：3.171
23、Savic MM et al. (2009) The differential role of α1- and α5-containing GABAA receptors in mediating diazepam effects on spontaneous locomotor activity and water-maze learning and memory in rats. The International Journal of Neuropsychopharmacology 12:1179-1193影响因 子：4.378
24、Walf AA et al. (2009) Chronic estradiol replacement to aged female rats reduces anxiety-like and depression-like behavior and enhances cognitive performance. Psychoneuroendocrinology 34:909-916影响因子：3.788
25、Wise LE et al. (2009) Hippocampal CB1 Receptors Mediate the Memory Impairing Effects of 9-Tetrahydrocannabinol. Neuropsychopharmacology 34:2072-2080影响因子：4.378
26、Newmyer BA & Cline MA (2009) Neuropeptide SF is associated with reduced food intake in chicks. Behavioral Brain Research 205:311-314影响因子：3.171
27、Cline MA et al. (2009) The Anorectic Effect of Neuropeptide AF is Associated with Satiety-Related Hypothalamic Nuclei. Journal of Neuroendocrinology 21:595-601影响因子： 3.252
28、Faure et al. (2009) Impaired neurogenesis, neuronal loss, and brain functional deficits in the APPxPS1-Ki mouse model of Alzheimer's disease. Neurobiology of Aging In Press影响因子：5.959
29、Gangitano D. et al. (2009) Progesterone modulation of alpha5 nAChR subunits influences anxiety-related behavior during estrus cycle. Genes Brain Behav [epub ahead of print] 影响因子：3.89 | |||
ANY-maze动物行为学实验室
一、实验室介绍
ANYmaze动物行为学实验室采用美国Stoelting公司生产的ANYmaze动物行为分析软件，硬件由江苏赛昂斯生物科技有限公司设计生产，完全无缝对接，中外结合，性价比最优！我司为您提供专业的实验室前期设计施工、技术支持、产品培训和良好的售后服务，确保您的实验室布局合理，功能完备。ANY-maze动物行为视频分析系统是一套通过视频摄像机和计算机，采用图像处理技术，自动跟踪和记录动物行为的通用型运动轨迹记录分析系统，可以应用在神经药理，学习记忆药理，抗衰老药理和新药神经系统一般药理毒理研究，也可用于神经科学基础研究。
二、实验应用
ANY-maze适用于morris水迷宫实验、开场实验、旷场实验、自发活动、悬尾实验、强迫游泳实验、明暗箱实验、T型迷宫、Y型迷宫、放射型迷宫、高架十字迷宫、八臂迷宫、Barnes迷宫、条件性位置偏爱实验、Zero迷宫、孔洞实验、新物体识别、社会交互实验等几乎所有的动物行为实验。
ANY-maze行为分析系统不但可以用于大小鼠、猫、犬、兔、豚鼠等小动物行为活动的跟踪监测，还可用于鱼、线虫、果蝇等微小生物行为活动的跟踪监测。
三、软件特点
支持三点识别（头部、重心、尾部）与轮廓识别同时实验，可探测动物的趋向轨迹，目标跟踪稳定可靠
测量精确，分析指标全面丰富，提供所在区域内的活动轨迹、时间、距离、潜伏期、速度、动/静状态等
在线实时图像分析和视频录像文件分析
采用极具人性化的树状结构体系，每个操作步骤均有详细对应的设置说明
多种实验启动/结束方式，方便实验操作
自带事件统计和分析功能
具有综合的报告和分析功能，自带超过30多种的统计检验
空间分辨率640×480，数字压缩录像功能
支持平均分段和任意分段方式查看统计实验数据
可以通过自定义事件（Event）和行为（Action），来完成各种复杂的实验程序控制
软件提供四种实验模式：视频轨迹模式、Freezing监测模式、No Tracking模式、No video模式
软件内置ANYmaze视频转换器，转换后支持所有的视频格式的离线分析。
四、实验室分类
学习记忆实验室
主要包括仪器有：Morris水迷宫、Barnes迷宫、穿梭实验系统、避暗实验系统、跳台实验系统、八臂迷宫和、Y迷宫、T迷宫等。
焦虑抑郁实验室
主要包括仪器有：高架十字迷宫、O迷宫、强迫游泳实验、悬尾实验、学习无助系统、饮水点击冲突系统等。
神经精神实验室
主要包括仪器有：自发活动实验、旷场实验、洞板实验系统、联合开场、斯金纳箱、场景恐惧系统、震惊实验系统等。
药物成瘾实验室
主要包括仪器有：大小鼠CPP条件性位置偏爱实验系统、CPA条件厌恶系统、自身给药系统等。
运动协调实验室
主要包括仪器有：大小鼠步态行为分析系统、转棒式疲劳仪、动物实验跑台等。
五、实验室布局
实验室布局根据客户需求及实际场地设计，下图为国内某客户的布局图：
六、指标参数
参数名称 | 总 | 自定义区域 | 百分比 | 首次进入 |
路程 | √ | √ | √ | × |
运动时间 | √ | √ | √ | √ |
静止时间 | √ | √ | √ |
|
进入次数 | √ | √ | × | × |
其他参数 | 理毛次数、僵直次数、僵直持续时间、运动轨迹 使用Anymaze软件发表论文列表（部分） 1、 Lee JY et al. (2009) Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus. Nature Medicine 15:91-96影响因子：27.553
2、 Belforte JE et al. (2009) Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nature Neuroscience (advanced online publication) 影响因子：14.345
3、 Imbimbo BP et al. (2010) CHF5074, a Novel γ-Secretase Modulator, Restores Hippocampal Neurogenesis Potential and Reverses Contextual Memory Deficit in a Transgenic Mouse Model of Alzheimer’s Disease. Journal of Alzheimer’s Disease 20: 159–173 影响因子：5.101
4、 Moore AH et al. (2009) Sustained expression of interleukin-1β in mouse hippocampus impairs spatial memory. Neuroscience 64:1484-95. 影响因子：3.556 5、 Pathipati P et al. (2009) Delayed and chronic treatment with growth hormone after endothelin-induced stroke in the adult rat. Behavioural Brain Research 204:93-101影响因子：3.171
6、 Epp JR and Galea LAM (2009) Hippocampus-dependent strategy choice predicts low levels of cell proliferation in the dentate gyrus. Neurobiology of Learning and Memory 91:437-446影响因子：3.757
7、 Frye CA and Paris JJ (2009) Infusions of bicuculline to the ventral tegmental area attenuates sexual, exploratory, and anti-anxiety behavior of proestrous rats. Pharmacology Biochemistry and Behavior 93:474-481影响因子：2.751
8、 Cline MA et al. (2009) LPLRFamide causes anorexigenic effects in broiler chicks and Bobwhite quail. General and Comparative Endocrinology 165:315-320 影响因子：2.654
9、 Layne JE et al. (2009) Central calcitonin exerts anoretic effects via the hypothalamus in chicks. Pharmacology Biochemistry and Behavior 92:433-438 影响因子：2.751
10、Llaneza DC and Frye CA (2009) Progestogens and estrogen influence impulsive burying and avoidant freezing behavior of naturally cycling and ovariectomized rats. Pharmacology Biochemistry and Behavior 93:337-342 影响因子：2.751
11、Janes AC et al. (2009) The involvement of type IV phosphodiesterases in cocaine-induced sensitization and subsequent pERK expression in the mouse nucleus accumbens. Psychopharmacology 206:177-185影响因子：3.676 12、Peric-Mataruga V (2009) Effects of ghrelin on the feeding behavior of Lymantria dispar L. (Lymantriidae) caterpillars. Appetite 53:147-150 影响因子：2.341
13、Booker L et al. (2009) Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception. Drug and Alcohol Dependence 105:42-47 影响因子：3.371
14、Thomas MB et al. (2009) Sex-specific susceptibility to cocaine in rats with a history of prenatal stress. Physiology & Behavior 97:270-277 影响因子：2.806
15、Capsoni S et al et al. (2009) Delivery of NGF to the Brain: Intranasal versus Ocular Administration in Anti-NGF Transgenic Mice. Journal of Alzheimer's Disease 16:371-388 影响因子：5.101
16、Cline MA et al. (2009) Satiety induced by central stresscopin is mediated by corticotrophin-releasing factor receptors and hypothalamic changes in chicks. Pharmacology Biochemistry and Behavior 92:663-669 影响因子：5.101
17、Walf AA and Frye CA (2009) Effects of two estradiol regimens on anxiety and depressive behaviors and trophic effects in peripheral tissues in a rodent model. Gender Medicine 6:300-311
18、Kourrich S and Thomas MJ (2009) Similar neurons, opposite adaptations: psychostimulant experience differentially alters firing properties in accumbens core versus shell. J Neuroscience 29:12275-12283影响因子：7.452
19、Covaceuszach Sonia et al. (2009) Development of a Non Invasive NGF-Based Therapy for Alzheimer's Disease. Current Alzheimer Research 6:158-170影响因子：4.132
20、Zhao W and Becker JB (2009) Sensitization enhances acquisition of cocaine self-administration in female rats: Estradiol further enhances cocaine intake after acquisition. Hormones and Behavior In Press影响因子：3.876
21、Schlosburg JE et al. (2009) Endocannabinoid modulation of ccratching response in an acute allergenic model: a new prospective neural therapeutic target for Pruritus. Journal of Pharmacology And Experimental Therapeutics 329:314-323影响因子：4.309
22、Guzmán CB et al. (2009) Sex-dependent effect of cyclooxygenase-2 inhibition on mouse spatial memory. Behavioural Brain Research 99:355-9影响因子：3.171
23、Savic MM et al. (2009) The differential role of α1- and α5-containing GABAA receptors in mediating diazepam effects on spontaneous locomotor activity and water-maze learning and memory in rats. The International Journal of Neuropsychopharmacology 12:1179-1193影响因 子：4.378
24、Walf AA et al. (2009) Chronic estradiol replacement to aged female rats reduces anxiety-like and depression-like behavior and enhances cognitive performance. Psychoneuroendocrinology 34:909-916影响因子：3.788
25、Wise LE et al. (2009) Hippocampal CB1 Receptors Mediate the Memory Impairing Effects of 9-Tetrahydrocannabinol. Neuropsychopharmacology 34:2072-2080影响因子：4.378
26、Newmyer BA & Cline MA (2009) Neuropeptide SF is associated with reduced food intake in chicks. Behavioral Brain Research 205:311-314影响因子：3.171
27、Cline MA et al. (2009) The Anorectic Effect of Neuropeptide AF is Associated with Satiety-Related Hypothalamic Nuclei. Journal of Neuroendocrinology 21:595-601影响因子： 3.252
28、Faure et al. (2009) Impaired neurogenesis, neuronal loss, and brain functional deficits in the APPxPS1-Ki mouse model of Alzheimer's disease. Neurobiology of Aging In Press影响因子：5.959
29、Gangitano D. et al. (2009) Progesterone modulation of alpha5 nAChR subunits influences anxiety-related behavior during estrus cycle. Genes Brain Behav [epub ahead of print] 影响因子：3.89 | |||
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